Zyloprim is used to treat gout, high levels of uric acid in the body caused by certain cancer medications, and kidney stones. Allopurinol is in a class of medications called xanthine oxidase inhibitors. It works by reducing the production of uric acid in the body. High levels of uric acid may cause gout attacks or kidney stones. Allopurinol is used to prevent gout attacks, not to treat them once they occur.

How Taken

 Take Zyloprim exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. Take each dose with a full glass of water. Also, to reduce the risk that kidney stones will form, drink 8 to 10 full glasses (8-ounce glasses) of fluid every day, unless your doctor directs otherwise. Take allopurinol with food or milk to lessen stomach upset. Store allopurinol at room temperature away from moisture and heat. Other uses for this medicine This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Warnings/Precautions

Before taking Zyloprim, 

* tell your doctor and pharmacist if you are allergic to allopurinol or any other medications. * tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: amoxicillin (Amoxil, Trimox); ampicillin (Polycillin, Principen); anticoagulants ('blood thinners') such as warfarin (Coumadin); cancer chemotherapy drugs such as cyclophosphamide (Cytoxan) and mercaptopurine (Purinethol); chlorpropamide (Diabinese); diuretics ('water pills'); medications that suppress the immune system such as azathioprine (Imuran) and cyclosporine (Neoral, Sandimmune); other medications for gout such as probenecid (Benemid) and sulfinpyrazone (Anturane); and tolbutamide (Orinase). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. 

* tell your doctor if you have or have ever had kidney or liver disease or heart failure. * tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking allopurinol, call your doctor. 

* you should know that allopurinol may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you. * ask your doctor about the safe use of alcoholic beverages while you are taking allopurinol. Alcohol may decrease the effectiveness of allopurinol.

Missed Dose

 Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Possible Side Effects

Zyloprim may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: * upset stomach * diarrhea * drowsiness Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately: * skin rash * painful urination * blood in the urine * irritation of the eyes * swelling of the lips or mouth * fever, sore throat, chills, and other signs of infection * loss of appetite * unexpected weight loss * itching Zyloprim may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

Storage

 Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

More Information

What other information should I know? Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to allopurinol. Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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