IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

TRETINOIN - TOPICAL (tret-ih-NO-in)

COMMON BRAND NAME(S): Retin-A

USES: This medication is used in the treatment of acne. It reduces the formation of pimples and promotes quick healing of pimples that do develop.

HOW TO USE: Patient instructions are available with the product. Read them carefully before using. Apply a thin layer to affected area at bedtime. Use a gauze pad or cotton swab to apply the liquid. Wash hands immediately after use. Using this medication more frequently or in excessive amounts does not improve the results, but may increase side effects. Avoid applying near the eyes, mouth, or open cuts since this medication can irritate sensitive skin. Even though acne may appear to worsen when the medication is first used, continue therapy. It may take three to six weeks before the full benefits of this medication are seen.

SIDE EFFECTS: Immediately after applying, the skin may feel warm or mild stinging or redness may occur. Some peeling of the skin may occur. These effects should subside as your skin adjusts to the medication. If they persist or become bothersome, inform your doctor. This medicine may also increase sun sensitivity. Notify your doctor if you experience: blistering, crusting, redness, severe burning or swelling of the skin. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: This medication can increase sensitivity to sunlight, wind and cold. Avoid prolonged exposure to the sun and sunlamps. Wear protective clothing and use an effective sunscreen. Use mild soap when washing your face. Do not wash face excessively. Abrasive soaps, cleansers, medicated creams or lotions can increase skin irritation. Consult your doctor or pharmacist about their use. Use other acne preparations with caution while using this medication. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if this medication passes into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription drugs you may use. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. This medicine may be harmful if swallowed. Symptoms of overdose may include excessive redness, peeling, and discomfort.

NOTES: Cosmetics may be used, but clean skin thoroughly before applying the medication.

MISSED DOSE: If you miss a dose, use it as soon as remembered; do not use if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

STORAGE: Store at room temperature away from sunlight.